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KMID : 0191120080230030540
Journal of Korean Medical Science
2008 Volume.23 No. 3 p.540 ~ p.543
Brunnera¡¯s Gland Hyperplasia: Treatment of Severe Diffuse Nodular Hyperplasia Mimicking a Malignancy on Pancreatic-Duodenal Area
Lee Woong-Chul

Yang Hyeon-Woong
Lee Yun-Jung
Jung Sung-Hee
Choi Gi-Young
Go Hoon
Kim An-Na
Cha Sang-Woo
Abstract
Brunnera¡¯s gland hyperplasia is a benign tumor of the duodenum and it is rarely associated with clinical symptoms. We report on a 64-yr-old man with Brunnera¡¯s gland hyperplasia who had undergone a duodenocephalo-pancreatectomy. The reason is that he presented upper gastrointestinal obstructive symptoms and the esophagogastroduodenoscopic finding revealed the lesion to be an infiltrating type mass on the second portion of the duodenum with luminal narrowing. An abdominal computed tomography showed a 2.5 cm-sized mass in the duodenal second portion with a suspicious pancreatic invasion and 7 mm-sized lymph node around the duodenum. Duodenocephalopancreatectomy was successfully performed. Histological examination revealed a Brunnera¡¯s gland hyperplasia. The final diagnosis was the coexistence of Brunnera¡¯s gland hyperplasia and pancreatic heterotopia with a pancreatic head invasion. The literature on Brunnera¡¯s gland hyperplasia is reviewed.
KEYWORD
Brunner Glands, Duodenal Neoplasms, Duodenal Obstruction
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